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Lin FU, Wu XIONG, Francisco DINI-ANDREOTE, Beibei WANG, Chengyuan TAO, Yunze RUAN, Zongzhuan SHEN, Rong LI, Qirong SHEN
《农业科学与工程前沿(英文)》 2020年 第7卷 第3期 页码 307-316 doi: 10.15302/J-FASE-2020328
Harnessing disease-suppressive microbiomes constitutes a promising strategy for optimizing plant growth. However, relatively little information is available about the relationship between bulk and rhizosphere soil microbiomes. Here, the assembly of banana bulk soil and rhizosphere microbiomes was investigated in a monoculture system consisting of bio-organic (BIO) and organic management practices. Applying BIO practice in newly reclaimed fields resulted in a high-efficiency biocontrol rate, thus providing a promising strategy for pre-control of Fusarium wilt disease. The soil microbiota was further characterized by MiSeq sequencing and quantitative PCR. The results indicate that disease suppression was mediated by the structure of a suppressive rhizosphere microbiome with respect to distinct community composition, diversity and abundance. Overall microbiome suppressiveness was primarily related to a particular set of enriched bacterial taxa affiliated with s, , , , and . Finally, structural equation modeling was used to show that the changes in bulk soil bacterial community determined its induced rhizosphere bacterial community, which serves as an important and direct factor in restraining the pathogen. Collectively, this study provides an integrative approach to disentangle the biological basis of disease-suppressive microbiomes in the context of agricultural practice and soil management.
关键词: agricultural practice bulk soil disease suppression rhizosphere ecology
Identification of cadmium-induced genes in maize seedlings by suppression subtractive hybridization
Quanlin DAI, Baifei HUANG, Zhongyi YANG, Jiangang YUAN, Junzhi YANG
《环境科学与工程前沿(英文)》 2010年 第4卷 第4期 页码 449-458 doi: 10.1007/s11783-010-0250-x
关键词:
Electromagnetic interference modeling and suppression techniques in variable-frequency drive systems
Le YANG, Shuo WANG, Jianghua FENG
《机械工程前沿(英文)》 2018年 第13卷 第3期 页码 329-353 doi: 10.1007/s11465-018-0466-1
Electromagnetic interference (EMI) causes electromechanical damage to the motors and degrades the reliability of variable-frequency drive (VFD) systems. Unlike fundamental frequency components in motor drive systems, high-frequency EMI noise, coupled with the parasitic parameters of the trough system, are difficult to analyze and reduce. In this article, EMI modeling techniques for different function units in a VFD system, including induction motors, motor bearings, and rectifier-inverters, are reviewed and evaluated in terms of applied frequency range, model parameterization, and model accuracy. The EMI models for the motors are categorized based on modeling techniques and model topologies. Motor bearing and shaft models are also reviewed, and techniques that are used to eliminate bearing current are evaluated. Modeling techniques for conventional rectifier-inverter systems are also summarized. EMI noise suppression techniques, including passive filter, Wheatstone bridge balance, active filter, and optimized modulation, are reviewed and compared based on the VFD system models.
关键词: variable-frequency drive (VFD) electromagnetic interference (EMI) motor drive modeling EMI noise suppression
Vibration suppression of speed-controlled robots with nonlinear control
Paolo BOSCARIOL,Alessandro GASPARETTO
《机械工程前沿(英文)》 2016年 第11卷 第2期 页码 204-212 doi: 10.1007/s11465-016-0380-3
In this paper, a simple nonlinear control strategy for the simultaneous position tracking and vibration damping of robots is presented. The control is developed for devices actuated by speed-controlled servo drives. The conditions for the asymptotic stability of the closed-loop system are derived by ensuring its passivity. The capability of achieving improved trajectory tracking and vibration suppression is shown through experimental tests conducted on a three-axis Cartesian robot. The control is aimed to be compatible with most industrial applications given the simplicity of implementation, the reduced computational requirements, and the use of joint position as the only measured signal.
关键词: industrial robot nonlinear control vibration damping model-free control motion control
刘江虹,金翔,廖光煊
《中国工程科学》 2010年 第12卷 第9期 页码 58-62
在研究传统细水雾添加剂的基础上,取长补短,采用物理工艺制备出新型复合添加剂,针对典型火源(酒精池火、煤油池火与木垛火),改变添加剂浓度开展了一系列灭火实验。结果表明:新型复合添加剂显著增强了细水雾的灭火性能,可提高灭火时间5~8倍。随着细水雾中添加剂含量的不断增加,油池火的灭火时间呈现出先快速下降,而后略微增长的趋势;而木垛火的灭火时间表现为平缓下降,并趋于稳定。含新型复合添加剂的细水雾灭火是物理化学复合作用机制,但主导灭火机理是燃料表面的冷却与隔离作用。
A convolutional neural network based approach to sea clutter suppression for small boat detection
Guan-qing Li, Zhi-yong Song, Qiang Fu,liguanqing09@nudt.edu.cn,songzhiyong08@nudt.edu.cn
《信息与电子工程前沿(英文)》 2020年 第21卷 第10期 页码 1413-1534 doi: 10.1631/FITEE.1900523
Haiqiao WEI, Jie YU, Lei ZHOU
《能源前沿(英文)》 2019年 第13卷 第4期 页码 691-706 doi: 10.1007/s11708-019-0621-3
关键词: high compression ratio knock Miller cycle split injection engine performance
Growth suppression of colorectal cancer expressing S492R EGFR by monoclonal antibody CH12
Qiongna Dong, Bizhi Shi, Min Zhou, Huiping Gao, Xiaoying Luo, Zonghai Li, Hua Jiang
《医学前沿(英文)》 2019年 第13卷 第1期 页码 83-93 doi: 10.1007/s11684-019-0682-z
Colorectal cancer (CRC) is a common malignant tumor in the digestive tract, and 30%–85% of CRCs express epidermal growth factor receptors (EGFRs). Recently, treatments using cetuximab, also named C225, an anti-EGFR monoclonal antibody, for CRC have been demonstrated to cause an S492R mutation in EGFR. However, little is known about the biological function of S492R EGFR. Therefore, we attempted to elucidate its biological function in CRC cells and explore new treatment strategies for this mutant form. Our study indicated that EGFR and S492R EGFR accelerate the growth of CRC cells in vitro and in vivo and monoclonal antibody CH12, which specifically recognizes an EGFR tumor-specific epitope, can bind efficiently to S492R EGFR. Furthermore, mAb CH12 showed significantly stronger growth suppression activities and induced a more potent antibody-dependent cellular cytotoxicity effect on CRC cells bearing S492R EGFR than mAb C225. mAb CH12 obviously suppressed the growth of CRC xenografts with S492R EGFR mutations in vivo. Thus, mAb CH12 may be a promising therapeutic agent in treating patients with CRC bearing an S492R EGFR mutation.
关键词: S492R EGFR ectodomain mutation colorectal cancer mAb CH12 immunnotherapy
Fault tolerant control strategy for modular PWM current source inverter
《能源前沿(英文)》 2023年 第17卷 第2期 页码 228-238 doi: 10.1007/s11708-022-0852-6
关键词: current source converter (CSC) fault-tolerant control space vector modulation active damping resonance suppression power quality
et’s disease in a Chinese population
null
《医学前沿(英文)》 2012年 第6卷 第4期 页码 354-359 doi: 10.1007/s11684-012-0234-2
Beh?et’s disease is defined as a multisystemic inflammatory disease. Although the precise pathogenesis and etiology is still a mystery, accumulating evidence shows that genetic variants of immune-related genes have a profound influence on the development of Beh?et’s disease. To explore the genetic factors for Beh?et’s disease, our group investigated the association of Beh?et’s disease with multiple immune response genes and has identified multiple Beh?et’s disease-related immunoregulatory pathways in the Chinese Han population. A large number of gene polymorphisms were studied including STAT4, IL23R, CD40, CCR1/CCR3, STAT3, OPN, IL17, JAK2, MCP-1, CTLA4, PD-1, PD-L1, PD-L2, TGRBR3, CCR6, PTPN22, FCRL3, IRF5, SUMO4 and UBAC2. Significant associations were found between Beh?et’s disease and STAT4, IL23R, CD40, CCR1/CCR3, STAT3, MCP-1, TGFBR3, FCRL3, SUMO4, UBAC2. These genetic predisposition studies support an important role for both lymphocyte differentiation as well as ubiquitination pathways. These findings are helpful in elucidating the pathogenesis of Beh?et’s disease and hopefully will allow the development of novel treatment regimes.
Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype
null
《医学前沿(英文)》 2013年 第7卷 第4期 页码 425-432 doi: 10.1007/s11684-013-0295-x
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality throughout the world and is mainly characterized by persistent airflow limitation. Given that multiple systems other than the lung can be impaired in COPD patients, the traditional FEV1/FVC ratio shows many limitations in COPD diagnosis and assessment. Certain heterogeneities are found in terms of clinical manifestations, physiology, imaging findings, and inflammatory reactions in COPD patients; thus, phenotyping can provide effective information for the prognosis and treatment. However, phenotypes are often based on symptoms or pathophysiological impairments in late-stage COPD, and the role of phenotypes in COPD prevention and early diagnosis remains unclear. This shortcoming may be overcome by the potential genotypes defined by the heterogeneities in certain genes. This review briefly describes the heterogeneity of COPD, with focus on recent advances in the correlations between genotypes and phenotypes. The potential roles of these genotypes and phenotypes in the molecular mechanisms and management of COPD are also elucidated.
关键词: chronic obstructive pulmonary disease heterogeneity phenotype genotype prediction
Acupuncture for the management of dry eye disease
《医学前沿(英文)》 2022年 第16卷 第6期 页码 975-983 doi: 10.1007/s11684-022-0923-4
Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development
Long-de Wang
《工程管理前沿(英文)》 2015年 第2卷 第1期 页码 2-12 doi: 10.15302/J-FEM-2015002
关键词: chronic disease prevention and control strategy and system construction
Astrocytes in depression and Alzheimer’s disease
《医学前沿(英文)》 2021年 第15卷 第6期 页码 829-841 doi: 10.1007/s11684-021-0875-0
关键词: astrocytes depression Alzheimer’s disease roles mechanisms
Minimal residual disease in solid tumors: an overview
《医学前沿(英文)》 2023年 第17卷 第4期 页码 649-674 doi: 10.1007/s11684-023-1018-6
关键词: MRD solid tumor CTC ctDNA
标题 作者 时间 类型 操作
Changes in bulk soil affect the disease-suppressive rhizosphere microbiome against Fusarium wilt disease
Lin FU, Wu XIONG, Francisco DINI-ANDREOTE, Beibei WANG, Chengyuan TAO, Yunze RUAN, Zongzhuan SHEN, Rong LI, Qirong SHEN
期刊论文
Identification of cadmium-induced genes in maize seedlings by suppression subtractive hybridization
Quanlin DAI, Baifei HUANG, Zhongyi YANG, Jiangang YUAN, Junzhi YANG
期刊论文
Electromagnetic interference modeling and suppression techniques in variable-frequency drive systems
Le YANG, Shuo WANG, Jianghua FENG
期刊论文
Vibration suppression of speed-controlled robots with nonlinear control
Paolo BOSCARIOL,Alessandro GASPARETTO
期刊论文
A convolutional neural network based approach to sea clutter suppression for small boat detection
Guan-qing Li, Zhi-yong Song, Qiang Fu,liguanqing09@nudt.edu.cn,songzhiyong08@nudt.edu.cn
期刊论文
Improvement of engine performance with high compression ratio based on knock suppression using Miller
Haiqiao WEI, Jie YU, Lei ZHOU
期刊论文
Growth suppression of colorectal cancer expressing S492R EGFR by monoclonal antibody CH12
Qiongna Dong, Bizhi Shi, Min Zhou, Huiping Gao, Xiaoying Luo, Zonghai Li, Hua Jiang
期刊论文
Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development
Long-de Wang
期刊论文